By Leonard C. Sperling
Diagnosing and treating hair issues is an integral part of either scientific and beauty dermatology perform. due to the fact that it is a topic that's hardly or purely superficially coated in the course of residency education, the pathologists and dermatopathologists who needs to review specimens submitted with a scientific analysis of hair disorder usually discover a hole of their wisdom. The filing dermatologist often needs to act as pathologist in addition to clinician. greater than only a publication on hair affliction, An Atlas of Hair Pathology with medical Correlations bridges that hole. the 1st finished evaluation of the microscopic pathology of hair ailment, this booklet serves as a primer, an atlas, and a reference. As a primer, it experiences very simple info, together with hair anatomy and the "nuts and bolts" of processing and comparing specimens. As an atlas, it really is wealthy in pictures demonstrating uncomplicated and complex histologic positive aspects of hair disorder. And, as a reference, it comprises updated info and a evaluate of simple scientific positive factors that offer a clinical-pathologic correlation. With 365 illustrations from the author's own selection of slides, An Atlas of Hair Pathology with medical Correlations is the main whole and "user-friendly" source on hair pathology on hand.
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Extra info for An Atlas of Hair Pathology with Clinical Correlations (The Encyclopedia of Visual Medicine Series)
The technique used by Headington and Whiting involves a single transverse slice about 1 mm below the epidermal surface. Both cut sides of the specimen are embedded down in the cassette. As the microtome cuts deeper into the tissue block, the sections become progressively more superficial in one half of the specimen and deeper in the other. Simply sectioning deeper into the block allows one to obtain sections as superficial or as deep as required. An alternative method is that of Frishberg and Sperling.
The ovals in this diagram overlap for several reasons. First, a diagnostic entity may share at least some clinical and/or histological features with another form of cicatricial alopecia. Second, it is possible that two ‘different’ entities may some day prove to be variations of the same disease (this concept is discussed in Chapter 23). Finally, the overlap of these ‘distinct’ entities serves as an admission that the conditions are poorly understood, and that their separation in this classification is provisional.
A generous amount of anesthetic (1–3 ml) should be injected into the deep dermis and superficial fat, and allowed to act for 15–30 minutes before the biopsy is performed. This will minimize bleeding. The blade of the punch biopsy tool should extend through the dermis down into the fat, so that intact bulbs of deeply rooted terminal hairs can be removed. A 4-mm biopsy wound can be easily closed with 3–0 suture because the needle can traverse the wound in a single pass. A suture color that contrasts with the patient’s hair will assist in suture removal 1 week after the biopsy is performed.
An Atlas of Hair Pathology with Clinical Correlations (The Encyclopedia of Visual Medicine Series) by Leonard C. Sperling