Download PDF by Guy F. Webster, Anthony V. Rawlings: Acne and its therapy

By Guy F. Webster, Anthony V. Rawlings

ISBN-10: 0824729714

ISBN-13: 9780824729714

Addressing some of the most ordinarily encountered stipulations obvious through the dermatologist, this resource analyzes the pathophysiology, overview, analysis, medical beneficial properties, and keep watch over of pimples. With full-color illustrations, this resource delves into the to be had healing procedures for tough instances of zits and scarring and offers professional discussions of administration regimens together with topical and systemic remedies, laser remedies, and new drugs.

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Extra resources for Acne and its therapy

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London: WB Saunders, 1975. 27. Williams M, Cunliffe WJ, Gould D. Pilosebaceous duct physiology I. Effect of hydration on pilosebaceous duct orifice. Br J Dermatol 1974; 90:631– 635. 28. Plewig G, Kligman AM. Acne, Morphogenesis and Treatment. Berlin: Springer-Verlag, 1975. 29. Knaggs HE, Hughes BR, Morris C, Holland DB, Wood EJ, Cunliffe WJ. Immunohistochemical study of desmosomes in acne vulgaris. Br J Dermatol 1994; 130:731– 737. 30. Rosenquist TA, Martin GA. Fibroblast growth factor signalling in the hair growth cycle: expression of the fibroblast growth factor receptor and ligand genes in the murine hair follicle.

179) analyzed the protein content of comedones and found both epidermal keratins and degraded keratins to be present in the comedones. Biochemical Changes in the Infundibulum During Comedogenesis The process of comedogenesis is thought to be due to hyperproliferation of ductal keratinocytes, inadequate separation of the ductal corneocytes, or a combination of both factors, resulting in microcomedones. Hyperproliferation of basal keratinocytes in acne has been demonstrated (180,181) and correlates with keratin 16 expression, a marker for hyperproliferation suprabasally (182).

Serri F, Huber WM. In Advances in Biology of Skin. Vol. 4. Oxford: Pergamon Press, 1963:1– 18. 17. Allen M, Grachtchouk M, Sheng H, et al. Hedgehog signaling regulates sebaceous gland development. Am J Path 2003; 163:2173– 2178. 18. Niemann C, Unden AB, Lyle S, Zouboulis ChC, Toftgard R, Watt FM. Indian hedgehog and beta-catenin signaling: role in the sebaceous lineage of normal and neoplastic mammalian epidermis. Proc Natl Acad Sci USA 2003; 100(suppl 1): 11873 – 11880. 19. Pie´rard GE. Follicle to follicle heterogeneity of sebum excretion.

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Acne and its therapy by Guy F. Webster, Anthony V. Rawlings


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